Public Policy and Advocacy

 

Medication and PN Component Shortages Readings and Reports

Medication Shortages

  • Baumer AM, Clark AM, Witmer DR, et al. National survey of the impact of drug shortages in acute care hospitals, Am J Health-Syst Pharm, 2004;61:2015-2022.
  • Chabner BA. Drug shortages-a critical challenge for the generic-drug market. N Engl J Med.2011;365:2147-2149.
  • Fox ER, Sweet BV, Jensen V. Drug shortages: A complex healthcare crisis. MayoClin Proc. 2014;89:361-373.
  • Hantel A, Siegler M, Hlubocky F, Colgan K, Daugherty CK. Prevalence and severity of rationing during drug shortages: A national survey of health system pharmacists. JAMA Intern Med. 2019;179:710–711.
  • Kaah R, Sweet RV, Reilly C, et al. Impact of drug shortages on US health system. Am J Health-Syst Pharm. 2011;68:1811-1819.
  • Mazer-Amirshahi M, Fox ER, Zocchi MS, Pines JM, van den Anker JN. Longitudinal trends in U.S. shortages of sterile solutions, 2001-17. Am JHealth-Syst Pharm. 2018;75:1903-1908.
  • McLaughlin M, Kotis D, Thomson K, et al. Effects of patient care caused by drug shortages: a survey. JManag Care Spec Pharm. 2013;19:783-788.
  • Shaban H, Maurer C, Willborn RJ. Impact of drug shortages on patient safety and pharmacy operation costs. Fed Pract. 2018;35: 24-31.
  • Woodcock J, Wosinska M. Eonomic and technological drivers of generic sterile injectable drug shortages. Clin Pharmacol Ther. 2013;93:170-176.
  • Hernandez I, Sampathkumar S, Good CB, Kesselheim AS, Shrank WH. Changes in drug pricing after drug Shortages in the United States. Ann Intern Med. 2018;75:1903-1908.

PN Component Shortages

  • Chan LN. Iatrogenic malnutrition: a serious public health issue caused by drug shortages. JPEN J Parenter Enteral Nutr.2013; 37:702-704.
  • Guenter P, Holcombe B, Mirtallo JM, Plogsted SW, DiBaise JK; Clinical Practice and Public Policy Committees, American Society for Parenteral and Enteral Nutrition. Parenteral nutrition utilization: response to drug shortages. JPEN J Parenter Enteral Nutr. 2014;38:11-12.
  • Gumpper KF. Drug shortages and training. JPEN J Parenter Enteral Nutr. 2012;36; 2 suppl: 42S-43S.
  • Hanson C, Thoene M, Wagner J, Collier D, Lecci K, Anderson-Berry A. Parenteral nutrition additive shortages: the short-term, long-term and potential epigenetic implications in premature and hospitalized infants. Nutrients. 2012;4:1977-1988.
  • Hassig TB, McKinzie BP, Fortier CR, Taber D. Clinical management strategies and implications for parenteral nutrition drug shortages in adult patients. Pharmacotherapy. 2014;34:72-84.
  • Holcombe B. Parenteral nutrition product shortages: impact on safety. JPEN J Parenter Enteral Nutr. 2012;36:2suppl,44S-47S.
  • Holcombe B, Mattox TW, Plogsted S. Drug shortages: Effect on parenteral nutrition therapy. Nutr Clin Pract. 2018;33(1):53-61.
  • Kaur K, O'Connor AH, Illig SM, Kopcza KB. Drug shortages as an impetus to improve parenteral nutrition practices. Am J Health Syst Pharm. 2013;70:1533-1537.
  • Mirtallo JM. The drug shortage crisis. JPEN J Parenter Enteral Nutr. 2011;35:433.
  • Mirtallo JM, Holcombe B, Kochevar M, Guenter P. Parenteral nutrition product shortages: the A.S.P.E.N. strategy. Nutr Clin Pract. 2012;27:385-391.
  • Mostafavifar L, Evans DC. Four‐oil lipid emulsion (Smoflipid) as a tool in managing parenteral nutrition shortages. Nutr Clin Pract. 2018;33:584.
  • Nystrom EM, Bergquist WJ, Wieruszewski PM, McMahon MM, Barreto EF. Parenteral nutrition drug shortages: A single-center experience with rapid process change. JPEN J Parenter Enteral Nutr. 2019;43(5):583-590.

Nutrient Deficiencies and Complications Associated with PNComponent Shortages

  • Sant VR, Arnell TD, Seres DS. Zinc deficiency with dermatitis in a parenteral nutrition–dependent patient due to national shortage of trace minerals. JPEN J Parenter EnteralNutr. 2016;40: 592-595.
  • Bible JO, Evans DC, Payne B, Mostafavifar L. Impact of drug shortages on patients receiving parenteral nutrition after laparotomy. JPEN J Parenter EnteralNutr. 2014; 38:65S-71S.
  • Davis, C, Javid PJ, Horslen S. Selenium deficiency in pediatric patients with intestinal failure as a consequence of drug shortage. JPEN J Parenter Enteral Nutr. 2014;38:115-118.
  • Franck AJ. Zinc deficiency in a parenteral nutrition–dependent patient during a parenteral trace element product shortage. JPEN J Parenter Enteral Nutr. 2014;38:637-39.
  • Palm E, Dotson B. Copper and zinc deficiency in a patient receiving long-term parenteral nutrition during a shortage of parenteral trace element products. JPEN J Parenter Enteral Nutr. 2015;39:986-989.
  • Centers for Disease Control and Prevention. Notes from the field: zinc deficiency dermatitis in cholestatic extremely premature infants after a nationwide shortage of injectable zinc—Washington, DC, December 2012 [published correction appears in MMWR Morb Mortal Wkly Rep. 2013 Mar; 15;62(10):196]. MMWR Morb Mortal Wkly Rep. 2013 Feb 22;62(7):136-137.
  • Ruktanonchai D, Lowe, M, Norton SA, et al. Zinc deficiency-associated dermatitis in infants during a nationwide shortage of injectable zinc - Washington, DC, and Houston, Texas, 2012-2013. [published (correction appears in MMWR Morb Mortal Wkly Rep. 2014 Jan 31;63(4):82]. MMWR Morb Mortal Wkly Rep. 2014 Jan 17;63(2):35-7.
  • Pramyothin P, Kim DW, Young LS, Wichabnsawakun S, Apovian CM. Anemia and leukopenia in a long-term parenteral nutrition patient during a shortage of parenteral trace element products in the United States. JPEN J Parenter Enteral Nutr. 2013;37; 425-429.
  • Corrigan M, Kirby DF. Impact of a national shortage of sterile ethanol on a home parenteral nutrition practice: A case series. JPEN J Parenter Enteral Nutr. 2012;36:476-480.

Reports