Transpyloric Feeding Found to Significantly Reduce Incidence of Ventilator Associated Pneumonia in Mechanically Ventilated Adults

February 10, 2016

Contact: Alena Rosen
P: 617-694-3595
E: [email protected]

Silver Spring, MD, February 10, 2016 – A systematic review published today in the OnlineFirst version of Nutrition in Clinical Practice (NCP), a research journal of The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.), found a significant reduction in incidences of ventilator-associated pneumonia (VAP) in mechanically ventilated (MV) adults though transpyloric feeding compared to gastric feeding. Prior to this study, Risk-Benefit Profile of Gastric vs. Transpyloric Feeding in Mechanically Ventilated Patients: a Meta-Analysis, the risk-benefit profile of these nutrition support systems in MV patients had not been definitively established. Though there were no other observed differences between the two nutrition support systems, the review opens the door for further study.

“Patients receiving MV in the intensive care unit are often in highly catabolic states due to critical illness, and may require extra nutrition support,” said Zhuo Li, MD, lead author of the review. “Because this nutrition support is critical, we conducted a meta-analysis to evaluate both the potential beneficial and adverse effects of gastric versus transpyloric feeding in these patients.”

The findings indicated a statistically significant reduction in VAP through transpyloric feeding compared to gastric feeding (RR 0.67, 95% CI: 0.53 to 0.85 P=0.001), however no statistically significant differences were found in in mortality rates (RR 1.08, 95% CI 0.86 to 1.36, P=0.49), duration of MV support (MD -0.16, 95% CI -0.75 to 0.43, P=0.59), length of stay in the intensive care unit (MD -0.91, 95% CI -2.75 to 0.94, P=0.34), or other MV related complications.

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About Nutrition in Clinical Practice (NCP)

Nutrition in Clinical Practice (NCP) is a peer-reviewed, interdisciplinary journal that publishes articles about the scientific basis and clinical application of nutrition and nutrition support. NCP contains comprehensive reviews, clinical research, case observations, and other types of papers written by experts in the field of nutrition and health care practitioners involved in the delivery of specialized nutrition support. NCP is an official journal of the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.).

About A.S.P.E.N.
The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) is dedicated to improving patient care by advancing the science and practice of nutrition support therapy and metabolism. Founded in 1976, A.S.P.E.N. is an interdisciplinary organization whose members are involved in the provision of clinical nutrition therapies, including parenteral and enteral nutrition. With more than 6,400 members from around the world, A.S.P.E.N. is a community of dietitians, nurses, nurse practitioners, pharmacists, physicians, scientists, students, and other health professionals from every facet of nutrition support clinical practice, research, and education. For more information about A.S.P.E.N., please visit