University of Saskatchewan Researcher Wins A.S.P.E.N. Award

March 1, 2016 Silver Spring, MD – Amanda Hall, MD, of the University of Saskatchewan, has been named a Research Trainee Award recipient by the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). The award is for her research on the negative results of aluminum (AI) contamination in parenteral nutrition (PN). Dr. Hall presented the research study, Aluminum Content in Parenteral Nutrition Negatively Affects Bile Acid Transporters, at A.S.P.E.N.’s Clinical Nutrition Week in Austin, Texas, January 16-19.

In this study, Dr. Hall and her colleagues assess the impact of AI contamination in parenteral nutrition to determine which bile acid transporters are negatively affected. . By understanding more about this adverse relationship, they were able to gain a better understanding of the pathophysiology that may lead to cholestasis.

Specifically, the study found that AI contamination has a negative effect on the apical bile acid transporters Mrp2 and Bsep. If these transporters are downregulated, the hepatocyte is at higher risk of accumulating bile acids, potentially leading to cholestasis.

Naming annual Research Trainee Award winners is at the core of the A.S.P.E.N. mission of improving patient care by advancing the science and practice of nutrition support therapy and metabolism.

“Recognizing and supporting leaders in the clinical nutrition field is essential in advancing new discoveries which, in turn, leads to optimizing patient care,” stated Debra BenAvram, CEO of A.S.P.E.N.. “We are honored to be a supporter of Dr. Hall’s research and to have the opportunity to formally recognize her important work.”

To learn more about Dr. Hall and her colleagues’ research, along with all the other presented research at Clinical Nutrition Week 2016, please click here.

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Founded in 1976, A.S.P.E.N. is an interdisciplinary organization whose members are involved in the provision of clinical nutrition therapies, including parenteral and enteral nutrition. With more than 6,000 members from around the world, A.S.P.E.N. is a community of dietitians, nurses, nurse practitioners, pharmacists, physicians, scientists, students, and other health professionals from every facet of nutrition support clinical practice, research, and education. For more information about A.S.P.E.N., please visit